NANOSUSPENSION TECHNOLOGY FOR POORLY SOLUBLE DRUGS: AN OVERVIEW
نویسندگان
چکیده
منابع مشابه
Nanocrystal Technology For Oral Delivery of Poorly Water-Soluble Drugs
Nanotechnology has been improving and has a variety of application fields. One of the major application areas of nanotechnology in pharmacy is nanoparticular drug delivery systems. Preparation of drug nanocrystals to improve the solubility of poorly water-soluble drugs for oral delivery is also one of the important applications. Nanocrystal dispersions comprise water, active drug substance and ...
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Solubility of drug plays critical role in achieving the optimum therapeutic levels of the drug in blood and thus bioavailability. There are many drugs of various therapeutic categories fall in BCS class II and IV as they lack solubility. For all these drugs dissolution is the big hurdle for the absorption process. Present review’s focus is mainly on novel techniques of improving the solubility ...
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A major hurdle in pharmaceutical formulation is water insolubility of most of drugs affecting their stability and bioavailability. If the drug is also insoluble in organic medium, it is difficult to deliver it in a sufficiently bioavailable form and hence it is a great challenge to formulation researchers to overcome such difficulty. Although some approaches are available for enhancing th...
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ژورنال
عنوان ژورنال: International Research Journal of Pharmacy
سال: 2020
ISSN: 2230-8407
DOI: 10.7897/2230-8407.110211